Association of Clinical Parameters and Prognosis with the Pretreatment Systemic Immune-inflammation Index (SII) in Patients with Gastric Cancer

This study explored the relationship between pretreatment systemic immune-inflammation index (SII) and overall survival (OS) in gastric cancer (GC) patients. A literature search was performed to find out articles that estimated of SII with specific clinical parameters OS GC Nine (including 10 studies) were included. total 3,850 cases eventually In patients, there no association gender (OR=0.991, p=0.944) or differentiation (OR=1.093, p=0.687). However, related depth tumor invasion (OR=0.340, p <0.001), lymph node metastasis (OR=0.447, <0.001) TNM stage (OR=0.361, The ORs 1-year, 3-year 5-year 0.467 (I2=0.0%; p=0.682), 0.355 (I2=85.6%; 0.507 (I2=56.4%; p=0.057). could be used as an indicator invasion, metastasis, more multi-centres researches are needed confirm these findings. Key Words: Systemic (SII), Prognosis, Gastric cancer.